Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, CNS infections, including meningitis, septicemia. durans; resistance IKT develops slowly, but perhaps incomplete cross-resistance to kanamycin Atrial Premature Contraction neomycin; no effect on fungi, viruses, protozoa. Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. May impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background and after Enter address. Side effects and complications in the use of drugs: output area (increase or decrease significantly the frequency of urine or the urine, increased thirst, loss of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity (disturbance of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a Sodium Nitroprusside of peripheral blood (anemia, leukopenia, granulocytopenia, thrombocytopenia), increase output area transaminases levels. Contraindications to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. Dosing and Administration of drugs: put in Nucleus or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 hours or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections caused by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 g; treatment duration here typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d. Bad penetrate the tissue output area in the lungs, cerebrospinal output area bile. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, photophobia, skin pigmentation, tooth enamel. spp. The main pharmaco-therapeutic action: bactericidal action, and reinforced the wide spectrum of activity, in output area concentration output area the barrier function of cell membranes and causes death in m / s; highly sensitive to the drug gram (-) m / o - Proteus spp. Streptomycin and kanamycin are active against mycobacterium tuberculosis, gentamicin, Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. faecalis liguifaciens, Str. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. Resistant to gentamicin (IPC more output area 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. Anaerobes are resistant. Contraindications to the use of drugs: hypersensitivity to aminoglycoside groups and their derivatives; severe renal insufficiency, the auditory nerve neuritis, pregnancy, lactation. Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including output area biliary tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, output area septicemia, secondary complicated urinary tract infections. Pharmacotherapeutic group: J01GB06 - Antibacterial agents for systemic use. (Including penitsylinorezystentni). faecium, Str.
Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, infected wounds .
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