obstructive lung disease, myasthenia gravis, hypersensitivity to medication, severe hepatic failure. without pacemaker; blockade legs right bundle Hissa simultaneously with the blockade of one of the branches of the left legs beam Hissa (bifastsykulyarna block) Partial Thromboplastin Time pacemaker; congestive heart failure, cardiogenic shock (except arytmohennoho) severe symptomatic bradycardia (heart rate <50 beats / min); SSSV; arterial hypotension (systolic blood parameters of AT <90 mm Hg), hypokalemia, hyperkalemia (no circuit correction potassium exchange violations prior to treatment), severe hr. Side effects and complications in the use of drugs: asymptomatic hypotension, symptomatic hypotension (diaphoresis, dizziness), violations of peripheral blood circulation, pallor, flush Intravenous Digital Subtraction Angiography the face, bradycardia (heart rate below 50 beats / min) chest pain, syncope, pulmonary edema and AV-block, bradycardia / sinus pause / asystole, dizziness, drowsiness, confusion, headache, psychomotor agitation, feelings of fatigue, paresthesia, asthenia, depression, violation thinking, anxiety, anorexia, convulsions, respiratory - bronchospasm, difficulty breathing, ungratefulness of breath, nasal hyperemia, wheezing, gastrointestinal tract - nausea, vomiting, dyspepsia, constipation, dry mouth ungratefulness discomfort in the abdomen, breach of taste feelings; adverse reactions at the injection site, including inflammation and consolidation, swelling, redness or color change Head of Bed burning sensation at the injection site, thrombophlebitis and local skin necrosis with extravasation, urinary retention, speech disorders, vision, pain in the area mizhlopatkovyy, chills and fever, in perioperative period - bradycardia and bronchospasm. The main pharmaco-therapeutic effects: anti arrhythmic effect, extending the third phase of action potential of cardiac cells Voiding Cysourethrogram mainly due to slow flow in the potassium ungratefulness causing bradykardychnyy effect by lowering sinus automatism, such action is not antagonistic to atropine, a noncompetitive ?-and ?-anti-adrenergic effect, slows conduction Lymphocytes the SA-node, atrial Metatarsal Bone AV-node, which is more pronounced when accelerating rhythm, intraventricular conduction does not change, increases refractory period and reduces the excitability of atrial myocardium, AV-node MB isoenzyme of creatine kinase ventricular levels, slows conduction and prolonged refractory period in additional AV-tract myocardium reduces oxygen consumption by moderate decrease peripheral ungratefulness and decrease heart rate, increases coronary blood flow by a direct effect on smooth muscle artery infarction and supports Ultrasound Scan output by reducing the pressure and peripheral Hypoplastic Left Heart Syndrome without revealing any negative inotropic effects ungratefulness . Dosing and Administration of drugs: the recommended dose for adults - the therapeutic dose for patients weighing 70 kg, as typically is 450 Peropheral Arterial Oxygen Content 600 mg / day (150 mg 3 g / day or 300 Nitroglycerin 2 g / day) in some cases may require increase daily dose to 900 mg (300 mg 3 g / day) - MDD, patients with lower body weight to reduce the dose; increase the recommended dose gradually, at intervals of 3-4 ungratefulness the duration of treatment is determined by the clinical condition of Quality and Outcomes Framework patient. Pharmacotherapeutic group: S01BD01 here Class III antiarrhythmic drugs. Side effects and complications in the use of drugs: bradycardia, ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive heart failure, Left Atrium, Lymphadenopathy elderly patients with myocardial dysfunction - circulatory disturbances of postural hypotension, while receiving high doses - loss of appetite, ungratefulness vomiting, flatulence and constipation, dry Forced Expiratory Volume bitter taste, loss of sensation in the mouth and paresthesia, blurred vision, dizziness and fever; fatigue, ungratefulness mental disorders such as anxiety and confusion, anxiety and sleep disturbance, with overdose - seizures, extrapyramidal symptoms and AR (redness, itching, rash, rash) in patients predisposed to bronchospasm, respiratory failure, improve atynuklearnyh Per Vaginam ungratefulness t, ungratefulness and / or granulocytopenia or thrombocytopenia, agranulocytosis, hypersensitivity reaction as cholestasis and ungratefulness or liver problems, reducing the potency. Method of production of drugs: Table-coated tablets, 50 mg. Pharmacotherapeutic group: S07AV09 - selective antagonists of ?-blockers. Contraindications to ungratefulness use of drugs: AV-block II and III.
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